Free BCEN Certified Flight Registered Nurse (CFRN) Practice Question

The most appropriate first-line treatment for an acute allergic reaction presenting with symptoms of anaphylaxis, such as hypotension, bronchospasm, and urticaria, is the administration of intramuscular epinephrine. Epinephrine acts rapidly to improve airway patency, reverse hypotension, and reduce urticaria. Antihistamines and steroids are supportive treatments but are not substitutes for the crucial first-line administration of epinephrine. IV fluids may be necessary for hypotension but should follow the administration of epinephrine.