Free BCEN Certified Flight Registered Nurse (CFRN) Practice Question

Norepinephrine is considered the first-line vasopressor for patients with septic shock who remain hypotensive despite adequate fluid resuscitation. It has potent alpha-adrenergic effects, leading to vasoconstriction and increased systemic vascular resistance, which help to improve blood pressure and perfusion. Epinephrine and dopamine can be considered in specific circumstances or as additional agents, but norepinephrine is preferred due to its more favorable balance of efficacy and side effects. Phenylephrine is typically a second-line option in patients with certain contraindications to norepinephrine.