A 35-year-old male patient exposed to a significant amount of ionizing radiation presents with erythema, pain, and blistering on the skin. Which of the following immediate interventions should be prioritized?
Administer broad-spectrum antibiotics to prevent infection.
Provide high-flow oxygen to manage potential respiratory distress.
Remove contaminated clothing and irrigate the affected area with copious amounts of water.
Initiate IV fluid resuscitation to manage potential shock.