A 35-year-old male patient exposed to a significant amount of ionizing radiation presents with erythema, pain, and blistering on the skin. Which of the following immediate interventions should be prioritized?
Remove contaminated clothing and irrigate the affected area with copious amounts of water.
Provide high-flow oxygen to manage potential respiratory distress.
Initiate IV fluid resuscitation to manage potential shock.
Administer broad-spectrum antibiotics to prevent infection.