An emergency department experiences a sudden influx of patients presenting with unexplained neurological symptoms, including tremors, confusion, and visual disturbances. Initial tests are inconclusive, and there's no apparent environmental cause. Which of the following actions should the emergency nurse prioritize to address this potential public health concern?
Immediately notify the local health department
Activate the hospital's syndromic surveillance protocol
Order comprehensive toxicology screens for all presenting patients
Isolate all affected patients as a precautionary measure