A 65-year-old patient with diabetes presents to the ER with a severe skin infection on his lower leg. Culture results confirm the presence of Methicillin-resistant Staphylococcus aureus (MRSA). What is the most appropriate initial action to manage his infection?
Immediately perform surgical debridement of the infected area.
Start treatment with amoxicillin.
Advise the patient to apply topical antiseptics and await further evaluation.
Begin empirical antibiotic therapy with Vancomycin or Linezolid.