A 62-year-old patient with a history of open-angle glaucoma presents to the ED with severe eye pain after accidentally instilling his wife's eye drops. He reports using timolol and latanoprost for his glaucoma. On examination, his intraocular pressure is 42 mmHg. Which of the following medications is most likely responsible for this acute elevation in intraocular pressure?
Brimonidine
Timolol
Cyclopentolate
Pilocarpine