A 25-year-old patient arrives in the emergency department with difficulty breathing, a wheezing sound upon auscultation, and a history of asthma. The patient's respiratory rate is 30 breaths per minute, SpO2 is 89% on room air, and they appear to be in acute distress. What is the BEST initial treatment option for this patient?
Administer inhaled anticholinergics
Administer high-flow oxygen
Begin nebulized short-acting beta-agonists
Give systemic corticosteroids